Stress due to work, studying for exams, raising children, increasing lifestyle issues, aging related weakness, complicated human relationships & unhealthy lifestyle practices are making the environment around us increasingly harsh
For those who want to spend every day in a healthy and positive manner, Nichi Glucan range of products are safe food supplements to maintain your immunity and overall well being
Stress due to work, studying for exams, raising children, increasing lifestyle issues, aging related weakness, complicated human relationships & unhealthy lifestyle practices are making the environment around us increasingly harsh
For those who want to spend every day in a healthy and positive manner, Nichi Glucan range of products are safe food supplements to maintain your immunity and overall well being
Nichi Glucans are a range of food supplements containing Beta Glucans. Beta glucans are naturally occurring polysaccharides with 1–3 β-glycosidic bonds classified as dietary fibre.
Among the beta glucans, β-1,3-1,6-type glucans are thought to be most useful for maintaining immunity.
In addition, β-1,3-1,6-glucan, has a molecular structure that binds to intestinal cells which in turn absorb them thereby acting on the body's immunity. Hence it is specifically called Biological Response Modifier Glucan (BRMG).
Nichi Glucans are a range of food supplements containing Beta Glucans. Beta glucans are naturally occurring polysaccharides with 1–3 β-glycosidic bonds classified as dietary fibre.
Among the beta glucans, β-1,3-1,6-type glucans are thought to be most useful for maintaining immunity.
In addition, β-1,3-1,6-glucan, has a molecular structure that binds to intestinal cells which in turn absorb them thereby acting on the body's immunity. Hence it is specifically called Biological Response Modifier Glucan (BRMG).
β-1,3-1,6-glucans are also present in shiitake mushrooms or produced by different yeasts. In the case of shiitake mushrooms, the Beta glucans must be extracted and purified to be made as an orally consumable product.
Nichi Glucan range of, β-1,3-1,6-glucans are unique as they are secreted by different novel strains of black yeast as an exo-polysaccharide and has a superior purity. So, its a pure BRMG without any of the commonly notified allergens. They are manufactured in a GMP certified facility in Japan.
Nichi Glucans are made from the black yeast because the BRMG can be manufactured efficiently by merely culturing the black yeast. Nichi Glucan range has four products; (i) Nichi Glucan, (ii) Nichi GLOW, (iii) Nichi Glucan REFIX & (iv) Neu REFIX.
β-1,3-1,6-glucans are also present in shiitake mushrooms or produced by different yeasts. In the case of shiitake mushrooms, the Beta glucans must be extracted and purified to be made as an orally consumable product.
Nichi Glucan range of, β-1,3-1,6-glucans are unique as they are secreted by different novel strains of black yeast as an exo-polysaccharide and has a superior purity. So, its a pure BRMG without any of the commonly notified allergens. They are manufactured in a GMP certified facility in Japan.
Nichi Glucans are made from the black yeast because the BRMG can be manufactured efficiently by merely culturing the black yeast. Nichi Glucan range has four products; (i) Nichi Glucan, (ii) Nichi GLOW, (iii) Nichi Glucan REFIX & (iv) Neu REFIX.
First, the medium used to cultivate Black Yeast is made. The Pristine natural water in Japan processed using our proprietary technology is used in the culture process.
Twenty eight commonly notified allergens are not used during the process, making Nichi Glucan range of products, a very safe food supplements.
First, the medium used to cultivate Black Yeast is made. The Pristine natural water in Japan processed using our proprietary technology is used in the culture process.
Twenty eight commonly notified allergens are not used during the process, making Nichi Glucan range of products, a very safe food supplements.
Next, the AFO-202 or N-163 black yeast strains are inoculated and cultured for the black yeast to secrete the β-1, 3-1, 6-glucan around it as an exo-polysaccharide. After the β-1, 3-1, 6-glucan is obtained, the entire produce is heat sterilized and filled in the containers.
From the cultivation to filling till packaging are undertaken in a GMP certified totally sterile condition, making it safely consumable either directly or mixed with food items.
Next, the AFO-202 or N-163 black yeast strains are inoculated and cultured for the black yeast to secrete the β-1, 3-1, 6-glucan around it as an exo-polysaccharide. After the β-1, 3-1, 6-glucan is obtained, the entire produce is heat sterilized and filled in the containers.
From the cultivation to filling till packaging are undertaken in a GMP certified totally sterile condition, making it safely consumable either directly or mixed with food items.
I no longer catch a heavy cold. In addition, the headache which becomes severe during sleeping is gone
Due to overweight, are you finding any improvement in your ability to move? I think so. I am able to move as when I was young.
I was afraid of getting stye and gingivitis from fatigue after childbirth, but I am OK now.
I used to be worried about my test values during routine medical check-up with my age, but now after Nichi Glucan I am better.
The children are taking it with their drink for their health and body management. As it is easy to drink, it helps.
As an athlete. I practice hard and lose weight. But I take Nichi Glucan to make sure that my immunity does not decrease. It is nice because it is portable and quick to drink anywhere.
I no longer catch a heavy cold. In addition, the headache which becomes severe during sleeping is gone
Due to overweight, are you finding any improvement in your ability to move? I think so. I am able to move as when I was young.
I was afraid of getting stye and gingivitis from fatigue after childbirth, but I am OK now.
I used to be worried about my test values during routine medical check-up with my age, but now after Nichi Glucan I am better.
The children are taking it with their drink for their health and body management. As it is easy to drink, it helps.
As an athlete. I practice hard and lose weight. But I take Nichi Glucan to make sure that my immunity does not decrease. It is nice because it is portable and quick to drink anywhere.
Remove glucan from bag
(Granule form of the products has a slight milk powder like taste)
Mix it with water, juice or Jam or any drink or consume as it is
One box contains 30 sachets for one month consumption, but please take 1-3 sachets a day according to your health condition
One box contains 30 sachets for one month consumption, but please take 1-3 sachets a day according to your health condition
Since it comes as Granules, you can consume it as it is, or mix it with other foods without disturbing the flavour (Dissolves in water, but becomes slightly gel-like)
Since it comes as Granules, you can consume it as it is, or mix it with other foods without disturbing the flavour (Dissolves in water, but becomes slightly gel-like)
Nichi Glucan has been approved as a food additive as “Aureobasidium (Black Yeast) culture solution”. It can be consumed safely by people of all ages from children to the elderly
Nichi Glucan has been approved as a food additive as “Aureobasidium (Black Yeast) culture solution”. It can be consumed safely by people of all ages from children to the elderly
What is ß-1, 3-16-Glucan?
ß-1, 3-16-Glucan is a polysaccharide in which glucose is linked in a ß-type structure.
Is it good for your health?
There are various types of ß-Glucans depending on the structure. Among them, ß-1, 3-16-Glucan is considered to be useful for maintaining immunity
Though ß-1, 3-16-Glucans are available in different sources, each has a unique structure, in spite of the same chemical formula,
[Chemical name] ß-1, 3-16-D-glucan [Molecular structure] (C6H10O5) n
Unique structural formula of Nichi Glucan produced by AFO-202 strains:
Why is it made from black yeast instead of Shiitake?
In order to obtain the desired effects of β-1, 3-1, 6-glucan, it must be in a molecular structure of Biological Response Modifier Glucan (BRMG) that binds to the intestinal cell receptor that in turn absorbs it. In the case of shiitake mushrooms, β-1, 3-1, 6-glucan must be extracted, purified and shaped into this molecular structure, but black yeast secretes the β-1, 3-1, 6-glucan as such in the BRMG form, outside its body, So, in the case of yeast the β-1, 3-1, 6-glucan need not be extracted or purified because it is not bound to other components. It becomes BRMG as it is.
Thus, by cultivating black yeast, β-1, 3-1, 6-glucan can be produced efficiently
Does Nichi Glucan contain Black Yeast?
Black Yeast biosynthesizes β-1, 3-1, 6-glucan outside its cells as an exo-polysaccharide. After the black yeast is cultured to produce β-1, 3-1, 6-glucan, the culture is sterilized by heating. Hence, there is no live organism in the Nichi Glucan range of products.
Is it safe to consume?
Nichi Glucans have been approved as a food additive “Aureobasidium culture solution”.
(Aureobasidium = Black Yeast)
[Existing additive list item list No.1] approved by the ministry of health, Govt of Japan in 1996.
There seems to be various types of β-glucan using Black Yeast?
Even if black yeast is used, different strains produce different types of β-1, 3-1, 6-glucans.
Nichi Glucan range of products use AFO-202 & N-163 strains of black yeast Aureobasidium Pullulans.
What is BRMG?
The β-1, 3-1, 6-glucans has a molecular structure that binds to the receptor of the intestinal cell that absorbs and acts on the body’s immunity. Hence it is called BRMG.
BRMG is a combination of the medical terms BRM (Biological Response Modifier) and G (Glucan)
How much BRMG is contained in one package?
Among the four products of Nichi Glucan range, two are produced by AFO-202 strain of Aureobasidium Pullulans: (i) Nichi Glucan ,(Granule, 42mg/1.0 gram in a sachet X 30 sachet per box), (ii) Nichi GLOW (Granule, 21mg/1.0 gram in a sachet X 30 sachet per box) and another two by N-163 strain: (iii) Nichi Glucan- REFIX (Gel, 60mg/10 gram in a sachet X 16 sachet per box), (iv) Neu REFIX (Gel, 48mg/8 gram in a sachet X 20 sachet per box).
How much should I take?
Nichi Glucan has 30 sachets for one month consumption, but many people take 1-3 sachets a day according to their health condition.
Although this product has been found to be very safe, please do not consume it in large quantities
It is tasteless and odorless, and it is granule type which is easy to consume by people of all ages from
Children to the elderly. You can enjoy Nichi Glucan by mixing it with any food
Contents 1g / bag (contains 42mg of BRMG)
30 bags / 1 box
30 days (sealed and stored in a low-temperature refrigerator)
Please consume immediately after opening
Glucan set
(Set of 3)
Contents 1g / bag (contains 42mg of BRMG)
90 bags / 3 boxes
30 days (sealed and stored in a low-temperature refrigerator)
Please consume immediately after opening